According to media reports, citing the Harney County Sheriff's office, Combs was identified as the driver and sole fatality connected with the accident in the desert about 90 miles (144 kilometers) south of Burns, Oregon, which is under investigation.
Founding Mythbusters host Adam Savage expressed his condolences on Twitter.
Kari Byron, another former host of Mythbusters, also tweeted her condolences. "So sad to hear about Jessi. She was a badass. Always pushing limits. Sending smiles into the universe for her", Byron said.
Terry Madden, a member of Combs' team, said she died "in a horrific accident", that he "was the first one there" and "did everything humanly possible to save her".
Jessi Combs hosted not only Mythbusters, but also Discovery's "Break Room," as well as "Overhaulin'" and "All Girls Garage" on Velocity.