Dave Chappelle was attacked on stage during his show in Los Angeles.
According to BuzzFeed News reporter, Brianna Sacks, who was present at the event, "a man charged and tackled" Chappelle at the end of the gig.
After the incident, the attacker was dragged off by security.
In turn, Dave Chappelle claimed that "it was a trans man".
The comedian has been criticised in the past for his trans jokes, which even led to a protest staged by Netflix staff.
The show was the inaugural live Netflix comedy festival.