NSDC Secretary Oleksiy Danilov was empowered to control the implementation of the decree, according to the document published by Zelensky's office.
The sanctions, among other things, involve blocking assets, restricting trade operations and preventing the withdrawal of capital outside Ukraine. In addition, the restrictions include a complete or partial ban on securities transactions.
Later in the day, Zelensky specified that the sanctions targeted 200 Russian nationals working for their country's nuclear industry.
The sanctions will remain in effect for 50 years.