Leicestershire Fire and Rescue is reportedly treating the incident as search and rescue operation. Several media cited witnesses reports of a large explosion on Hinckley Road.
Leicestershire police later reported a "major accident" in the area, and that the roads had been closed. The police also asked people to avoid the area.
The representatives of local hospitals reported the number of people hospitalized following the incident to be six, with two of them in critical condition. Earlier, medics reported that four people were hospitalized in critical condition.
Earlier, there were several reports that the explosion rocked a convenience store and destroyed a flat along with it. The Leicestershire police department has said in a press release later that there was no indication that this incident was related to terrorism.
"The cause of the explosion will be the subject of a joint investigation by the police and Leicestershire Fire and Rescue Service. We would ask that the media and public do not speculate about the circumstances surrounding the incident but at this stage there is no indication this is terrorist related," the press release, published on late Sunday, read read.