The company joined in the verbal abuse, posting a picture of January signings Pierre-Emerick Aubameyang and Henrik Mkhitaryan side by side with the caption "#YoPierre… we've made a massive mistake here pal."
The Gunners have only won twice since the arrival of the attacking duo, and to make matters worse, Aubameyang missed a penalty 51 minutes into the second leg of the EFL Cup.
SportPesa have since deleted both tweets.
READ MORE: Paul Pogba to Real Madrid?
Arsene Wenger has dismissed concerns about his newcomers' form, saying "they need some time to adapt" after the 3-0 loss.