The country has seen weeks of deadly protests against President Daniel Ortega and his policies, in particular in the area of social security, in the capital and other cities. Dozens of people were reportedly killed.
Students, private sector workers and others joined the demonstration organized by the church, the ITV broadcaster reported.
On Monday, private businesses held another protest.
The reform proposed by the government increased taxes paid by workers and employers and cut down pensions. After a series of violent clashes between protesters and the police, Ortega publicly announced last week that he would not go through with the reform. The president also proposed to hold meetings with representatives of various sectors of the society.
However, the peaceful demonstrations continued. The protesters are now demanding Ortega's resignation.
On Friday, National Assembly head Gustavo Porras announced the creation of a truth commission to look into what happened during the protests, including into the high number of deaths.