According to the Sun, 21 people were injured after the bus hit a concrete structure on the tarmac which was part of roadworks. The accident happened at 2.28 am on the E40 Highway in Belgium near the town of Aalter.
According to the Police spokesman, driving times and rest periods of the driver were in order.
The bus was carrying passengers from Amsterdam to London.
According to reports, the damaged bus was removed from the road around 6 am.