"30 people, including students of Konkan Krishi Vidyapeeth, fatally injured after a bus falls down a mountain road on Mumbai-Goa highway near Raigad. Rescue operation underway," Tawde said on Twitter.
The passengers were reportedly heading to the town of Mahabaleshwar for a weekend picnic.
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Indian Prime Minister Narendra Modi has expressed his condolences over the tragic incident.