"The Union of the Comoros is experiencing gunfire, political unrest, and infrastructure disruptions", the alert said. "US Government personnel have been ordered to depart the country".
The embassy warned citizens to avoid crowds and demonstrations, have evacuation plans that do not rely on US government assistance and review personal security plans.
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According to the embassy, the Union of the Comoros has experienced demonstrations, civil unrest, and roadblocks impacting travel since the 24 March elections.
"Chief of Mission official and personal travel to Comoros is restricted until further notice except for mission-critical travel deemed essential by the Deputy Chief of Mission", the US Embassy said.