According to the paper, the accident took place on Friday at around 3:50 p.m. local time (1:50 p.m. GMT).
There were 49 schoolchildren aged between 16 and 18, a driver and six teachers inside the bus.
Apart from 21 children, the bus driver and one of the teachers were injured. Six minors sustained major wounds and were hospitalised.
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Moreover, the 80-year-old driver of the car and one of its passengers were gravely injured as well.
Two rescue helicopters, seven ambulance cars, and nine firefighting vehicles were at the scene.