The trains collided at around 4 a.m. local time on Thursday (23:00 GMT on Wednesday), according to the broadcaster Geo News.
A total of 11 people were killed and 67 others, including 11 children, were injured as a result of the railroad accident that took place in the Sadiqabad Tehsil area, the news channel specified.
A rescue operation is underway to help people get out of the wrecked train and recover the victims' bodies, the broadcaster said.
The passenger train is believed to have swtiched to a wrong track while it was passing near a railway station where the freight train was stationed on a loop line, Geo News stated.
Up to four passenger cars have derailed as a result of the collision, the broadcaster added.
Pakistani Railways Minister Sheikh Rasheed Ahmed said in comments to the broadcaster that the collision had been caused by negligence. The minister added that an investigation into the accident had been launched.