At around 2:45 a.m. Thursday, Congressman Cummings passed away at Johns Hopkins Hospital, CNN and other media reported on Thursday.
Earlier, he hadn't returned to work after a medical procedure that he said would only keep him absent for a week, according to the Washington Post.
Elijah Cummings hasn't taken part in a roll call vote since 11 September.
Cummings has had health issues in recent years. He was using a wheelchair to get around. According to media reports, he was previously treated for heart and knee problems.
He was born on 18 January 1951 in Baltimore.