According to The Himalayan Times, the bus skidded off the road and fell down from about 500-metre height in Sindhupalchowk district.
The bus was carrying pilgrims after visiting Kalinchowk Temple. The police said that the number of casualties was likely to increase. Local residents have joined the rescue operation and those injured are being transferred to nearby hospitals.
The bus driver reportedly left the site of the incident, while his assistant was severely injured.