The tremors were recorded at 9:33 local time (01:33 GMT) in Tingri County, which is under the administration of the prefecture-level city of Xigaze.
The epicentre of the earthquake was located at a depth of 10 kilometre (more than 6 miles).
The shake was reportedly felt in eastern Nepal, including the capital Kathmandu.
There is no information about any damage or victims caused by the earthquake.
The Tibet Autonomous Region lies along the border between the Eurasian tectonic plate and the Indian plate. The latter has been moving to the north for some 100 million years, colliding with the Eurasian plate. This colossal geological process, which resulted in the formation of the Himalayas and other nearby mountain ranges, causes powerful earthquakes.