"As for the head of state, his health protection is already at the maximum level", Peskov said in a televised interview when asked whether the president’s health protection would be stepped up.
On Thursday, 54-year-old Mishustin said he had tested positive for the virus and was self-isolating. Deputy Prime Minister Andrei Belousov has been appointed as his temporary replacement.
The Russian president accepted Belousov's candidacy and signed the corresponding decree.
Russia has registered 114,431 confirmed cases, including 1,169 deaths and 13,220 people who have defeated the disease, according to the official data.