According to the CBC broadcaster, the demonstrations across the city have been peaceful, with participants carrying signs that read "No Justice No Peace."
Videos of protests in several areas appeared in social media.
One of the protesting groups was recorded singing a birthday song in memory of Breonna Taylor, an African-American woman killed by police in Louisville, who would have turned 27 today.
"It is just really great to see it in such a peaceful manner. It carries so much weight," Matt Moyer, the Toronto police inspector, said, quoted by the broadcaster.
Moyer took a knee alongside a protester at the US Consulate and voiced his full support for the participants of the rallies.
"I want them to know I am walking with them and I support their cause and I support exactly what they are doing. And I think the fact that they are showing such a demonstration for change, it is what we want," the inspector added.
The death of African American George Floyd on May 25 in the US city of Minneapolis has sparked a worldwide movement against police brutality, racism and social injustice. The video showing white police officer Derek Chauvin kneeling on Floyd's neck after the latter had been arrested has been widely circulated. Alongside demonstrations in all 50 of the United States and almost every major urban area, mass protests have also taken place in Greece, Italy, the United Kingdom, Denmark, Germany, France, New Zealand, Australia, Canada, and many other countries.