"More alarmingly, China-US relations, one of the most consequential bilateral relationships in the world, is faced with the most severe challenge since the establishment of diplomatic ties," Wang said, as quoted by the Foreign Ministry in a press release.
The minister added that some politicians from the United States are trying to "portray China as an adversary, and even an enemy," as they seek to limit China’s development and Beijing-Washington cooperation.
"First, China and the US should not seek to remodel each other. Instead, they must work together to find ways to peaceful coexistence of different systems and civilizations," Wang said.
The minister also said that Beijing’s policy towards Washington remains the same, as the country is aiming to improve relations with "goodwill and sincerity."
The US-China relations have been deteriorating recently amid difference over trade, Hong Kong’s status and COVID-19 response, among others.
Washington has also accused Beijing of withholding information during the early stages of the COVID-19 outbreak and claimed that it has evidence that the virus originated in a Chinese laboratory. Beijing has denied all accusations.