The decision came after US President Donald Trump announced on Friday that he and First lady Melania Trump tested positive for novel coronavirus.
Plexiglass should be used as a barrier between the two debate participants as well as the debate moderator Susan Page, the report said.
The Commission also decided to nearly double the distance between the participants from seven to 13 feet, the report added.
Earlier on Monday, Democratic presidential nominee Joe Biden said he is ready to engage US President Donald Trump in a second debate despite concerns about the possibility of contracting the novel coronavirus.