A Friday release issued by Blue Origin via Twitter underscores the devastation felt across the company for the sudden loss.
"He brought so much life and energy to the entire Blue Origin team and to his fellow crewmates. His passion for aviation, his charitable work, and his dedication to his craft will long be revered and admired."
The light plane left Essex County Airport in Caldwell, New Jersey, on what should have been a routine trip to Sussex Airport but was reported missing, media reported. Emergency workers found its remains at Hampton Township 60 miles west of New York City, the reports said.
De Vries, 49, founded Medidata Solutions, a successful advanced technology company, and was a trustee at Carnegie Mellon University in Pittsburgh. He traveled aboard Blue Origin's New Shepard spacecraft on October 13, spending more than 10 minutes in space after launching along with Shatner and others.
Flight instructor Thomas Fischer, 54, was also killed in the crash, the reports said.