“The prevailing perception in the international media and scientific literature is that MPXV [monkeypox virus] is endemic in people in some African countries. However, it is well established that nearly all MPXV outbreaks in Africa prior to the 2022 outbreak have been the result of spillover from animals to humans, and only rarely have there been reports of sustained human-to-human transmissions,” the scientists wrote.
The virus is related to smallpox and has a similar appearance and mostly similar symptoms, but is far less virulent. It has been observed to have a mortality rate of between 3.6% and 10% in the African countries where it is endemic, but a much lower mortality rate in more developed nations. Scientists believe the smallpox vaccine will also protect against monkeypox but have not recommended mass vaccination as of yet.