Explosions were reported in the vicinity of the capital on Friday morning, although the targets of the strike were as yet unclear. At least seven explosions were reported, in the areas of Al-Sidiyah Zainab and Qudsayya.
Video shared online was purported to be of the Syrian air defenses, but the veracity of the video was uncertain.
Syrian officials said after the strikes that most of the incoming missiles had been successfully intercepted, but that three soldiers had nonetheless been killed and seven others injured.
Israel has for years carried out strikes against targets in Syria, which it typically claims are Iranian and intended for use in attacking Israel. Jerusalem does not have formal diplomatic relations with either Iran or Syria.