Police received reports of a fight and shooting at Henley Road in the town of Ilford in east London at 00:16 local time (23:16 GMT on Monday). Police officers found three males with gunshot injuries at the scene.
"An investigation is ongoing after two males were fatally shot, and a third left critically injured, following an incident in Ilford," the police said in a statement.
Due to the investigation, the roads near the scene are blocked. There have been no arrests yet, according to the statement.