"I hope you’re having a good flight, Volodymyr. I’m thrilled to have you here. Much to discuss," Biden tweeted.
The two leaders will discuss a range of topics, including battlefield strategy in Ukraine, energy, and sanctions against Russia, among other matters, a senior US official told reporters.
The US president is also expected to announce a new $2 billion security assistance package that will include a Patriot air defense system, the official said.
Zelensky is due to visit the White House on Wednesday afternoon before delivering an address to a joint session of the US Congress later in the evening, according to US officials.