"Biden and the deep state are just itching to get us into a serious conflict with Iran. We have to tell them no," Massie said on X.
The US has bolstered its military presence in the Middle East, including deploying additional F-22 Raptor jets, amid tensions between Iran and Israel.
On Thursday, a senior administration official said that the consequences of a direct Iranian attack on Israel would be significant.
However, Massie included a meme in his statement, which joked that the US must finish dealing with its involvement in the Ukraine conflict before engaging in a conflict with Iran.
"You have to finish your Ukraine before you can have any Iran," the meme says.
Last month, a commission on the US National Defense Strategy established by the Congress found that the US risked losing in the event of multiple conflicts with peer and near-peer adversaries.