Confidence in the current government was expressed by 151 lawmakers out of 299 who took part in the vote.
Opening the debates ahead of the vote, Tsipras asked the lawmakers to support his Cabinet and allow him to finalize important reforms by the end of his four-year term.
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After winnig a vote of confidence, Alexis Tsipras said that the passed voting was "a vote for stability", Reuters reported.
"We received a vote of confidence with our only concern to continue to address the needs and interests of the Greek people," Tsipras told journalists.
Previously, Tsipras called for a vote of confidence for his government, after ANEL — one of the ruling coalition parties — left the government. ANEL's move was the result of a clash of opinions on the issue of Macedonia changing its name to the Republic of North Macedonia.