According to the Heraldo newspaper, the plane, which was bound for the northern Honduran city of Trujillo, crashed less than half a mile from the coast.
Initially, one person survived the crash and was rushed to hospital, but later died of wounds.
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According to local authorities, the model of the plane was a Piper PA-32-260. The plane reportedly crashed into the sea shortly after taking off from the island of Roatan.