Russia repelled seven Ukrainian counterattacks near the Rozovka and Vodyanoye around Avdeyevka, the MoD noted.
"The enemy lost up to 450 soldiers, a tank, four infantry fighting vehicles, six armored combat vehicles, five military vehicles, a Grad multiple rocket launcher system, as well as a D-30 howitzer," the MoD said in a statement.
Ukraine has also lost more than 425 soldiers in the Donetsk region and up to 210 soldiers, as well as two tanks south of Donetsk, the ministry added.