The Bezymyanny volcano erupted Sunday, a spokesman said. He added that the eruption resulted in a plume, stretching for up to 700 kilometers (435 miles) to the Pacific.
Official have instructed local residents to avoid leaving their homes, because particles of volcanic ash, spread in the air, could cause poisoning and serious diseases.
Experts said the plume poses no immediate threat to local residents, but that there is a danger to aircraft flying near the mountain.
According to experts, there are more that 150 volcanoes on Kamchatka, 29 of them are active.
Volcano's activity has recently increased on the Kamchatka peninsula.
Experts registered up to 450 minor quakes daily near Karymsky, Kamchatka's most active volcano, in the southeast of the peninsular, which rises to 1,536 metres (5,039 feet) above sea level.
This year more than 1,200 people, including 542 children, were evacuated from the north of the Kamchatka peninsula after a series of earthquakes. The first 7.8-magnitude quake, the strongest in the Koryak Autonomous Area in the north of the peninsular since 1900, injured 31 people on April 21. It also damaged about 380 houses and 25 administrative facilities in four other towns.