The quake measuring 6.5 on the Richter scale, with an epicenter at the Peloponnese Peninsula some 205 km (127 miles) east of the capital Athens, destroyed over 200 houses and 800 other buildings.
Around 20 people have been hospitalized with serious injuries.
Three villages in southwestern Greece on Monday were evacuated after seismologists forecast a strong aftershock in the quake-stricken areas.
The national highway connecting the capital Athens with the southern city of Patras was blocked by falling rocks. The government has pledged to allocate up to $20,000 to people whose homes sustained severe damage.
This January, a 6.5 earthquake jolted the Peloponnese Peninsula, but no deaths were reported. The last deadly earthquake hit Greece in 1999, and resulted in 143 deaths.