The November 5 state of the nation address, twice postponed from October 23 and 30, will be Medvedev's first, and the 15th delivered to parliament by a Russian head of state.
"This document will include answers to a number of quintessential questions that the country faces," Medvedev promised in his latest video blog posted on his website on Sunday.
In particular, he highlighted the Caucasus crisis. "We cannot avoid its repercussions, not only for our country but for the entire world," he said.
Medvedev said his address would contain the usual issues. "But life is so eventful that in every new address, naturally, these issues take on quite different dimensions," ha said, giving the global financial crisis as an example.
He also said he would touch upon ways to improve the life of Russians, reform of the armed forces, and international issues.
Georgia attacked its breakaway republic of South Ossetia on August 8 in a bid to bring it back under central control.
Moscow subsequently launched an operation to repel Georgian forces from the region and later recognized both South Ossetia and another breakaway republic, Abkhazia, as independent states.
The presidents of Russia, Armenia and Azerbaijan met in Moscow on Sunday to try and find a resolution to the Nagorny Karabakh conflict. The meeting ended with Medvedev, Armenian President Serzh Sargsyan and Azerbaijani leader Ilham Aliyev signing a declaration agreeing to continue seeking a resolution to the conflict.
Nagorny Karabakh, a region in Azerbaijan with a largely Armenian population, declared its independence from Azerbaijan to join Armenia in 1988 and has been a source of conflict ever since.