Igor Andreev crashed out of the first round at the clay court Estoril Open in Portugal on Tuesday, losing in three sets to Spanish qualifier Inigo Cervantes.
The match ended 6-4, 3-6, 6-3, lasting two hours and continuing the Russian world No. 78's underwhelming 2012.
He failed to qualify for the Australian Open, and was dumped out of the Barcelona Open in round two by Milos Raonic of Canada last week.
Spaniard Juan Martin Del Potro is top seed in Estoril, which has a €400,000 prize fund.