Late goals for midfielders Bibras Natkho and Roman Eremenko brought Rubin Kazan a hard-fought 2-0 home win against Dynamo Moscow in the Russian Premier League on Sunday.
The defeat leaves Dynamo at the bottom of the table, with no points from four games and no permanent coach.
Sergei Silkin resigned following a 4-0 derby humiliation to Spartak last week and his former assistant Dmitri Khohlov led the team in his second match in charge after thrashing Dundee United 5-0 in the Europa League on Thursday.
Rubin now sit second in the league after a third consecutive win following their opening 2-1 defeat to FC Krasnodar.
Natkho scored on 78 minutes from a free-kick, curling around the wall and inside the post from some 30 yards, leaving goalkeeper Roman Berezovsky completely stranded.
Two minutes into stoppage time, Eremenko made sure of the win with a long-range low shot into the corner that left the Armenian goalkeeper with no chance.
Rubin had the initiative throughout the game and could have opened the scoring on 23 minutes if not for Berezovsku, who stopped a long-range strike by ex-Dortmund forward Nelson Haedo Valdez.
Dynamo had their best chance on 40 minutes, when Rubin goalkeeper Sergey Ryzhikov denied a mighty shot from distance by ex-Germany striker Kevin Kuranyi.
On 58 Dynamo midfielder Igor Semshov pulled off a goalline clearance to deny ex-Valencia defender Ivan Marcano, before Turkey winger Gokdeniz Karadeniz fired past the post on the rebound.
Earlier on Sunday, stubborn resistance from Mordovia Saransk thwarted the Amkar Perm attack and earned the newly-promoted minnows a point for a goalless draw and the only goal from Zoran Tosic helped CSKA Moscow to scrape a 1-0 win against big-spending Anzhi.
On Saturday, Zenit St. Petersburg hammered in five goals as they demolished 10-man Spartak Moscow to go clear at the top, while Lokomotiv Moscow clung on for a 2-2 draw with Alania Vladikavkaz and Terek Grozny beat FC Volga 2-0.
On Friday, FC Kuban defeated rivals FC Krasnodar 2-1 in a derby clash.
Later Sunday Rostov play Krylya Sovetov in the final match of the fourth round.