Japanese Scientists Make First Step to Cure Kidney Disease

© China DailyA group of Japanese scientists have successfully created a nephron, the basic structural unit of a kidney, from rat stem cells, a first step for curing chronic kidney diseases, Okayama University reported on Tuesday.
A group of Japanese scientists have successfully created a nephron, the basic structural unit of a kidney, from rat stem cells, a first step for curing chronic kidney diseases, Okayama University reported on Tuesday. - Sputnik International
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Japanese scientists consider their experiment to be a first step towards kidney tissue recreation, and, if they are able to recreate the results using human stem cells, it may offer a cure for chronic kidney disease.

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MOSCOW, November 26 (Sputnik) – A group of Japanese scientists have successfully created a nephron, the basic structural unit of a kidney, from rat stem cells, a first step for curing chronic kidney diseases, Okayama University reported on Tuesday.

"Creating organs out of stem cells has been a dream of humanity for a long time. The successful creation of retina cells, brain and liver fragments is an already known fact. But for the first time in the world we succeeded to recreate a structure amazingly matching to a real kidney structure," states the Okayama University.

During the experiment, scientists took stem cells of a rat kidney and added 5 types of protein. Three weeks later they recreated the structure of a nephron. Japanese scientists consider the experiment to be a first step towards kidney tissue recreation, and, if they are able to recreate the results using human stem cells, it may offer a cure for chronic kidney disease.

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The primary function of the nephron, the tissue comprising the basic structural unit of a kidney, is blood purification. An average human kidney contains around a million nephrons.

Japan has been a leader in the creation of organs using stem cells. Studies in this field reached new phase in 2012, when Japan's Professor Shinya Yamanaka won a Nobel Prize in 2006 for creating a stem cell out of human skin cells. These cells were later called induced pluripotent stem cells or iPSCs. Scientists have since used the new technology to create the cells of heart muscle, bowel, pancreas, retina, blood, skin, nerves, female egg and sperm.

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