With her trademark lolling tongue and waddling gait, Lil Bub is probably one of the most famous cats in the world. She was born a runt in an otherwise healthy litter, with a number of genetic anomalies such as a short lower jaw which causes her tongue to loll constantly, extra toes and big, bulging eyes. The cat also has an extreme case of dwarfism and suffers from a bone disease called osteopetrosis.