The Saudi-led coalition of mainly Gulf countries launched a military campaign on Wednesday targeting Houthi militants, who control large parts of Yemen.
Scores of people have been reported killed following the airstrikes on the capital city of Sanaa.
"It is obvious when diplomats are gathering somewhere they talk about it [Yemen]. But we have said many times that our issue at the table is the nuclear negotiations. Our negotiations are limited to nuclear issue," Zarif told journalists.
Iran and the P5+1 countries, comprising Russia, China, the United States, the United Kingdom, France and Germany, have been trying to reach an agreement guaranteeing a peaceful nature of the Iranian nuclear program for more than a year.
A final deal is expected by July 2015 while a political framework for the agreement is anticipated by the end of March.