The demonstration has been called as a consequence of Panama Papers leak, which involves Cameron's family and earnings.
On Thursday night the prime minister admitted that he and his wife sold shares for more than £30,000 in a fund set up in Panama by his father, who passed away in 2010.
Right now at Downing St: 'David Cameron must resign!' #resigncameron pic.twitter.com/y6IPv0Au2d
— Jen Wilton (@GuerillaGrrl) 9 April 2016
The protest will end only after he resigns, according to organisers.
#resigncameron pic.twitter.com/PbhtECKZBX
— Tomas Off-Shore Fund (@M0by_Duck) 9 April 2016
On Sunday, Germany's Sueddeutsche Zeitung published alleged documents, obtained in a data leak by Panama firm Mossack Fonseca, that suggested that the prime minister's father Ian Cameron was a director of the offshore investment fund Blairmore Holdings, run from the Bahamas.
Does anyone have tickets to the Conservative Party Conference 2016? I've heard it's in Panama this year. #resigncameron
— Steph (@Stephsputnik) 9 April 2016
Cameron's first reaction on Tuesday was to say he did not own any shares. However, he admitted on Thursday he had sold his share worth 30,000 pounds ($42,000 at the current exchange rates) in the Blairmore Holdings shortly before assuming the prime minister's office.