"The United Kingdom will no longer be a part of the European Union and the procedures, provided by the treaty, will be implemented quickly, such are the rules, such are the consequences," Hollande said in a televised address.
On Thursday, UK citizens voted on their country's fate in the European Union. On Friday, voting data indicated that Britain voted to leave the bloc.
"The UK referendum has put Europe before a difficult challenge. [Europe] must show its resolution and strength to do everything possible to overcome the economic and financial risks caused by Brexit," Hollande said adding that some measures have already been taken.
According to Hollande, France and the United Kingdom will continue cooperating as friendly nations.
Hollande added Friday he will travel to Berlin on Monday to meet with German Chancellor Angela Merkel and Italian Prime Minister Matteo Renzi following the British vote to exit the European Union.
Hollande made the announcement at the Elysee Palace nearly simultaneously with Merkel, who added that she also invited European Council President Donald Tusk to attend the meeting addressing the Brexit referendum.