"It is not possible to respect this ultimatum … It is not serious," Andre Antoine said in a televised comment on Bel RTL radio.
European Council President Donald Tusk has reportedly given the Wallonia region until late Monday to figure out its stance on the Comprehensive Economic and Trade Agreement, which will abolish 98 percent of tariffs.
The Walloon government voted against the trade deal for fear it would water down EU labor, consumer and environmental protections, and give too much power to multinationals.
Antoine argued that, although the French-speaking region loved Canada, a decision to wave the trade pact through would open the way for similar deals with the United States, Japan, or China.
"It is the future of globalization that is at stake. And we want it to be regulated not only by the 'survival-of-the-fittest' law," he stressed.
The CETA was to be signed at Thursday’s EU-Canada summit. It needs to be ratified by all 28 EU member states. But under the Belgian federal laws, every region has a right to reject the agreement.