"There has been an incident at Bulawayo (White City Stadium) where the president was addressing a rally. This is now a police issue but the president is safe at Bulawayo State House," the president's spokesman, George Charamba, said, as quoted by Reuters.
Constantino Chiwenga, one of Zimbabwe's vice presidents, and his wife were slightly wounded in the explosion, whereas the country's political commissar, Rugeje, has reportedly sustained injuries, Reuters reported, citing sources close to the president.
According to The Herald newspaper, Zimbabwe's other vice president, Kembo Mohadi, suffered leg injuries and the minister of water, environment and climate, Oppah Muchinguri-Kashiri, was also wounded in the blast.
Reacting to the incident Mnangagwa stated that the blast took place just inches away from him, but "it wasn't his time". He noted that this is not the first assassination attempt he experienced, adding that there were "so many" of them.
"The campaign so far has been conducted in a free and peaceful environment, and we will not allow this cowardly act to get in our way as we move towards elections," Mnangagwa stated in a Facebook post.
Footage shown by the state TV broadcaster depicts Mnangagwa who had just finished his speech and was ready to leave the stage. When the explosion occurred, the broadcast was interrupted by the provider.
In November, Mugabe, 93, who served both as president and prime minister, stepped down. Mnangagwa, who previously served as vice president, was sworn in as Mugabe's successor. One of Mnangagwa's key promises was to revive the country's ruined economy, as well as hold free and fair elections.
Earlier in the day, a similar blast hit a rally in Ethiopia where the country's prime minister, Abiy Ahmed, was addressing supporters.