The latest round of skirmishes comes as the nation is celebrating Jerusalem Day, commemorating the establishment of Israel's control over the Old City in the wake of the Six-Day War in 1967.
The clashes occurred outside the city's main holy site for Muslims - the Al-Aqsa Mosque. The protesters threw stones at the police, prompting the officers to use tear gas, stun grenades, and rubber bullets.
The bloody clashes saw over 300 Palestinians injured, with 228 taken to hospital, while the Israeli side reported 21 wounded police officers and seven injured civilians.
Sputnik invites you to have a look at scenes of the unrest that rocked the Holy City on Monday.
© REUTERS / Ammar AwadA cameraman is helped by a Palestinian after falling to the ground during clashes with Israeli police at the compound that houses the Al-Aqsa Mosque, known to Muslims as the Noble Sanctuary and to Jews as the Temple Mount, in Jerusalem's Old City, 10 May 2021.
A cameraman is helped by a Palestinian after falling to the ground during clashes with Israeli police at the compound that houses the Al-Aqsa Mosque, known to Muslims as the Noble Sanctuary and to Jews as the Temple Mount, in Jerusalem's Old City, 10 May 2021.
© AFP 2023 / Emmanuel DunandA Palestinian argues with Israeli security forces in Jerusalem's Old City ahead of a planned march to commemorate Israel's takeover of Jerusalem in the 1967 Six-Day War.
A Palestinian argues with Israeli security forces in Jerusalem's Old City ahead of a planned march to commemorate Israel's takeover of Jerusalem in the 1967 Six-Day War.
© AP Photo / Mahmoud IlleanPalestinians clash with Israeli security forces at the Al Aqsa Mosque compound in Jerusalem's Old City on Monday.
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© AP Photo / Mahmoud Illean
Palestinians clash with Israeli security forces at the Al Aqsa Mosque compound in Jerusalem's Old City on Monday.
© REUTERS / Ammar AwadA wounded Palestinian is evacuated during clashes with Israeli police at the compound that houses the Al-Aqsa Mosque.
A wounded Palestinian is evacuated during clashes with Israeli police at the compound that houses the Al-Aqsa Mosque.
© AP Photo / Ohad ZwigenbergAn Israeli police officer stands with pistol pointed at a Palestinian man, centre, next to a Jewish driver who was attacked by Palestinian protesters near Jerusalem's Old City, Monday, 10 May 2021.
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© AP Photo / Ohad Zwigenberg
An Israeli police officer stands with pistol pointed at a Palestinian man, centre, next to a Jewish driver who was attacked by Palestinian protesters near Jerusalem's Old City, Monday, 10 May 2021.
© REUTERS / Ammar AwadPalestinians run away as Israeli police fire a stun grenade.
Palestinians run away as Israeli police fire a stun grenade.
© REUTERS / Ammar AwadIsraeli police detain a Palestinian during clashes.
Israeli police detain a Palestinian during clashes.
© AFP 2023 / Aahmad GharabliPalestinians run for cover from tear gas fired by Israeli security forces.
Palestinians run for cover from tear gas fired by Israeli security forces.
© REUTERS / Ronen ZvulunSmoke disperses from a stun grenade fired by Israeli security forces amid Israeli-Palestinian tensions.
Smoke disperses from a stun grenade fired by Israeli security forces amid Israeli-Palestinian tensions.
© AP Photo / Mahmoud IlleanPalestinians clash with Israeli security forces at the Al Aqsa Mosque compound in Jerusalem's Old City.
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© AP Photo / Mahmoud Illean
Palestinians clash with Israeli security forces at the Al Aqsa Mosque compound in Jerusalem's Old City.