According to the ministry, an unknown man opened fire from one of the houses in Borodin Street in Yekaterinburg.
"As a result, a girl and an employee of the Rosgvardiya [Russian National Guard] were injured, they are receiving medical assistance," the report read.
According to the Health Ministry of the Sverdlovsk region, the girl who suffered in the shooting remains in critical condition, and the security troop sustained a wound to his leg.
According to eyewitnesses, about 50 shots were fired during the incident.
The shooter has been detained, the interior ministry said.