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Over 60 Nations Tracking Spread of New ‘Orthrus’ Subvariant Stemming From Omicron Covid

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Virus 2021 - Sputnik International, 1920, 01.02.2023
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The new variant has been detected in 67 countries, with authorities in China, the US and UK warning that Orthrus could become the new dominant method of SARS-CoV-2 infection three years into the COVID-19 pandemic.
The scientific name for the new subvariant of the Omicron variant of SARS-CoV-2 is CH.1.1, but it’s been given the nickname “Orthrus,” after the two-headed dog from Greek mythology that was slain by the hero Heracles.
Chinese health authorities said on Tuesday that the new subvariant was capable of getting around immune responses, even those induced by mRNA-based vaccines. However, they predicted the recent mass outbreak in China would prevent Orthrus from causing a wave of reinfections.
A health worker checks the temperatures of visitor at the entrance of a Community Testing Centre in Hong Kong, China. After days of rapidly increase of positive COVID-19 cases, the Hong Kong government set up testing facility centers where people can be tested for COVID-19 and obtain the result within 24 hours. - Sputnik International, 1920, 25.01.2023
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“Despite an increased ability to resist immune responses and a higher transmissibility, which might increase breakthrough infection and reinfection risks, the population in China has a high level of neutralizing antibodies,” the Chinese Center for Disease Control and Prevention (CDC) said in a statement.
“There is a certain effect on cross protection, and it will not cause a large-scale domestic outbreak in the short term,” they added, referring to the immune benefits of prior infection.
Chinese health authorities added that the Covid outbreak there continues to be driven by BA.5.2 and BF.7, two other subvariants of Omicron, but they have begun detecting more cases of Orthrus in recent months. It was first detected in Southeast Asia late last year.
Although it is derived from the Omicron variant of the virus, scientists report it has a rare mutation in its spike protein - the device the virus uses to infect a cell - that they haven’t seen since the earlier Delta variant. Delta and Omicron evolved separately, meaning this mutation’s appearance is an example of convergent evolution.
However, a recent preprint paper published by Ohio State University researchers reported Orthrus’ ability to evade antibodies is “extraordinary.” They found the subvariant could evade both monovalent and bivalent mRNA vaccines, as well as antibodies produced by prior infection with BA.4 or BA.5, two other Omicron subvariants.
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In the United Kingdom, the Health Security Agency (UKHSA) said Orthrus is behind one-third of infections over the last week, and they are also watching XBB.1.5, a US-originating strain that was nicknamed “Kraken” last year and now accounts for the majority of US cases.
The US CDC estimates that just 1.5% of cases in the US are caused by Orthrus.
US President Joe Biden made confusing remarks about the pandemic on Wednesday, telling US media that "the Covid Emergency will end when the Supreme Court ends it. We've extended it to May the 15th to make sure we get everything done. That's all.”
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