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Arctic Sea Cucumber Delivers One-Two Punch to Triple-Negative Breast Cancer

© Sputnik / Alexander Liskin / Go to the mediabankSea cucumber
Sea cucumber - Sputnik International, 1920, 29.09.2026
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Two compounds that can stop the growth of one of the most aggressive forms of breast cancer have been derived from a sea cucumber (Ocnus glacialis) by researchers at the Elyakov Pacific Institute of Bioorganic Chemistry of the Russian Academy of Sciences.
Compounds named glacialisosides A and B - derived from the sea cucumber found in the cold waters of the Chukchi Sea — showed particularly strong activity against triple-negative breast cancer, revealed the research.
These compounds selectively target malignant cells while having little effect on healthy breast cells:
at concentrations below 0.2 μM, they stopped cancer-cell division
at 1 μM, they completely blocked the growth of cancer-cell colonies
The Russian scientists say the findings point toward a new class of anti-cancer drugs based on glycosides derived from Arctic marine invertebrates.
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